Dr. Michael T. Reinartz
connective, creative, dedicated
Personal Information
I am a fully trained biomedical scientist with deepened expertise in pharmacology.
Currently, I am working as an Associate Director German Market Access. I use my skills as an interdisciplinary, project-oriented scientist for medical writing and project-managing tasks within the value dossier team at Xcenda GmbH in Hannover, Germany.
I received my doctor´s degree at the Medical School Hannover. As part of my thesis studies at the Institute for Pharmacology, I gained deepened knowledge in the fields of drug target interactions and receptor pharmacogenetics, focusing on seven transmembrane domain receptors (7TMR).
More specifically, I analyzed β₂-adrenoceptor-mediated signal transduction. The β₂-adrenoceptor is pathophysiologically relevant e.g. in case of bronchial asthma. My studies add to the receptor-pharmacological concept of functional selectivity. Functional selective (or biased ) ligands may be exploited to achieve highly selective drug effects and, thus, improved drug safety with less adverse effects. Further, I collaborated with allergy geneticists. Here we linked genomic and pharmacological profiling of the β₂-adrenoceptor in 60 volunteers. Such pharmacogenomical data may help to stratify treatment groups and create a basis for a more effective, personalized asthma therapy.
Employment
• Project lead and management related to German early benefit assessments process according to § 35a SGB V (AMNOG) • Consulting and medical writing in context of market access and early benefit assessment in Germany • Go-To-Person for digital topics and Volunteer-Time-Off-activities
Research Assistant / PhD Student
Institute of Pharmacology, Hannover Medical SchoolI deepened my research of molecular-pharmacological properties of the β₂-adrenergic receptor.
I generated pharmacological profiles of enantiopure β₂-adrenergic drugs using a recombinant receptor system.
Research Internship
Institute of Biochemistry I, Heinrich Heine University, DüsseldorfI purified and characterized a membrane transporter protein.
B. sc. Student
Department of Chemical Biology, Max Planck Institute of Molecular Physiology, DortmundI researched binding partners to an enzyme using co-immunoprecipitation.